4SC-202 free base ( 4SC202; 4SC-202; 4SC 202; domatinostat )

Catalog No. M16538 CAS No. 910462-43-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

4SC-202 free base
Note

Research use only, not for human use.
Brief Description

4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively.
Description

4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
Synonyms

4SC202; 4SC-202; 4SC 202; domatinostat
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

HDAC3; HDAC2; HDAC1
Research Area

Cancer
Indication

——

CAS Number

910462-43-0
Formula Weight

447.51
Molecular Formula

CHNOS
Purity

>98%(HPLC)
Solubility

DMSO:82 mg/mL (183.2 mM);Ethanol:<1 mg/mL;Water:<1 mg/mL
SMILES

O=C(NC1=CC=CC=C1N)/C=C/C2=CN(S(=O)(C3=CC=C(C4=CN(C)N=C4)C=C3)=O)C=C2.O=S(C5=CC=C(C)C=C5)(O)=O
Chemical Name

(E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide.

1.Henning SW, et al. 22nd EORTC-NCI-AACR symposium. 2010. Abstract # 178.

Calculator

molnova catalog